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A convincing answer could come from suitable site mutations in these proteins causing a decreased affinity for GSSG

Adenosine receptors in neuropsychiatric disorders: fine regulators of neurotransmission and potential therapeutic targets

Sample collection Sow blood was collected via the ear vein on gestation day 110 (G110) and lactation day 14 (L14), with piglet jugular vein blood sampled from mean-weight-matched littermates

Although the mechanisms involved are not clearly understood, further research is needed to uncover the molecular mechanisms by which certain diuretics disrupt fuel metabolism and contribute to metabolic disturbances